GMHI: Gut Microbiome Health Index

Related tags

MiscellaneousGMHI
Overview

GMHI: Gut Microbiome Health Index

Anaconda-Server Badge Anaconda-Server Badge Anaconda-Server Badge Anaconda-Server Badge Anaconda-Server Badge

Description

Gut Microbiome Health Index (GMHI) is a robust index for evaluating health status based on the species-level taxonomic profile of a stool shotgun metagenome (gut microbiome) sample.

Installation

To avoid dependency conflicts, create an isolated conda environment and install gmhi

  1. Install via conda
conda create --name gmhi_env -c danielchang2002 python=3.7 gmhi
  1. Activate environment
conda activate gmhi_env

Usage

usage: gmhi [-h] [-o OUTPUT] --fastq1 FASTQ1 --fastq2 FASTQ2

DESCRIPTION:
GMHI version 1.0
Gut Microbiome Health Index (GMHI) is a robust index for evaluating 
health status based on the species-level taxonomic profile of a stool 
shotgun metagenome (gut microbiome) sample.

AUTHORS:
Daniel Chang, Vinod Gupta, Jaeyun Sung

USAGE:
GMHI is a pipeline that takes as input two raw fastq files generated 
from a paired end sequence, performs quality control, estimates microbial 
abundances, and returns as output a health index score.

* Profiling a metagenome from raw reads:
$ gmhi --fastq1 metagenome1.fastq --fastq2 metagenome2.fastq

optional arguments:
  -h, --help            show this help message and exit
  -o OUTPUT, --output OUTPUT
                        Output file name

required named arguments:
  --fastq1 FASTQ1       first input fastq file
  --fastq2 FASTQ2       second input fastq file

Example

Directory structure:

.
├── metagenome1.fastq
└── metagenome2.fastq

Command:

gmhi --fastq1 metagenome1.fastq --fastq2 metagenome2.fastq -o GMHI2.txt

Result:

.
├── GMHI.txt
├── abundance.txt
├── metagenome1.fastq
└── metagenome2.fastq

where GMHI2.txt is a text file with a single line containing the health index score of the metagenome, and abundance.txt is a tsv containing the estimated microbial abundances.

Runtime

Runtime depends on the size of the input metagenome and the system specs.

On a 2019 MacBook Pro with a 2.3 GHz 8-Core Intel Core i9 processor and 16GB of RAM, a single run of gmhi on an input metagenome of 4 GB takes 29 minutes.

Note: the initial run on any machine will take extra time because databases will need to be downloaded and installed before the actual computation.

Owner
Daniel Chang
Daniel Chang
Checkers Project Built Using Python

Checkers Project Built Using Python

Meekness Anyaeche 1 Nov 08, 2021
A python package that adds "docs" command to disnake

About This extension's purpose is of adding a "docs" command, its purpose is to help documenting in chat. How To Load It from disnake.ext import comma

7 Jan 03, 2023
🔩 Like builtins, but boltons. 250+ constructs, recipes, and snippets which extend (and rely on nothing but) the Python standard library. Nothing like Michael Bolton.

Boltons boltons should be builtins. Boltons is a set of over 230 BSD-licensed, pure-Python utilities in the same spirit as — and yet conspicuously mis

Mahmoud Hashemi 6k Jan 06, 2023
my own python useful functions

PythonToolKit Motivation This Repo should help save time for data scientists' daily work regarding the Time Series regression task by providing functi

Kai 2 Oct 01, 2022
Wisdom Tree is a concentration app i am working on.

Wisdom Tree Wisdom Tree is a tui concentration app I am working on. Inspired by the wisdom tree in Plants vs. Zombies which gives in-game tips when it

NO ONE 241 Jan 01, 2023
Collatz Sanısını Test Eden Ve Kanıtlayan Bir Python Programı

Collatz Sanısı Collatz Sanısını Test Eden Ve Kanıtlayan Bir Python Programı. Kullanım Terminalde: 1- git clone https://github.com/detherminal/Collatz-

Cemal Mert 2 May 07, 2022
Kellogg bad | Union good | Support strike funds

KelloggBot Credit to SeanDaBlack for the basis of the script. req.py is selenium python bot. sc.js is a the base of the ios shortcut [COMING SOON] Set

407 Nov 17, 2022
Advanced Developing of Python Apps Final Exercise

Advanced-Developing-of-Python-Apps-Final-Exercise This is an exercise that I did for a python advanced learning course. The exercise is divided into t

Alejandro Méndez Fernández 1 Dec 04, 2021
Github dorking tool

gh-dork Supply a list of dorks and, optionally, one of the following: a user (-u) a file with a list of users (-uf) an organization (-org) a file with

Molly White 119 Dec 21, 2022
Nateve transpiler developed with python.

Adam Adam is a Nateve Programming Language transpiler developed using Python. Nateve Nateve is a new general domain programming language open source i

Nateve 7 Jan 15, 2022
carrier.py is a Python package/module that's used to save time when programming

carrier.py is a Python package/module that's used to save time when programming, it helps with functions such as 24 and 12 hour time, Discord webhooks, etc

Zacky2613 2 Mar 20, 2022
It is a personal assistant chatbot, capable to perform many tasks same as Google Assistant plus more extra features...

PersonalAssistant It is an Personal Assistant, capable to perform many tasks with some unique features, that you haven'e seen yet.... Features / Tasks

Roshan Kumar 95 Dec 21, 2022
To attract customers, the hotel chain has added to its website the ability to book a room without prepayment

To attract customers, the hotel chain has added to its website the ability to book a room without prepayment. We need to predict whether the customer is going to reject the booking or not. Since in c

Taychinov Evgeniy 0 Aug 04, 2022
A python tool that creates issues in your repos based on TODO comments in your code

Krypto A neat little sidekick python script to create issues on your repo based on comments left in the code on your behalf Convert todo comments in y

Alex Antoniou 4 Oct 26, 2021
aaencode for python,把python代码转换为颜文字

py-aaencode aaencode for python,把python代码转换为颜文字 compile.py: 将python编译成颜文字,编译结果有随机性,可以选择BPE词表压缩代码 compile_min.py: 最小化的编译器 compiled_min.txt: 编译得到的最小的com

11 Dec 30, 2021
An open-source hyper-heuristic framework for multi-objective optimization

MOEA-HH An open-source hyper-heuristic framework for multi-objective optimization. Introduction The multi-objective optimization technique is widely u

Hengzhe Zhang 1 Feb 10, 2022
Subcert is an subdomain enumeration tool, that finds all the subdomains from certificate transparency logs.

Subcert Subcert is a subdomain enumeration tool, that finds all the valid subdomains from certificate transparency logs. Table of contents Setup Demo

A3h1nt 59 Dec 16, 2022
pspsps(1) is a compyuter software to call an online catgirl to the Linux terminyal.

pspsps(1): call a catgirl from the Internyet to the Linux terminyal show processes: ps show catgirls: pspsps —@ Melissa Boiko 32 Dec 19, 2022

My collection of mini-projects in various languages

Mini-Projects My collection of mini-projects in various languages About: This repository consists of a number of small projects. Most of these "mini-p

Siddhant Attavar 1 Jul 11, 2022
GNU/Linux'u yeni kurulumu bitirmiş olarak açtığınızda sizi karşılayacak bir uygulama.

Hoş Geldiniz GNU/Linux'u yeni kurulumu bitirmiş olarak açtığınızda sizi karşılayacak bir uygulama.

Alperen İsa 96 Oct 30, 2022